NUBAIN 20 MG (NALBUPHINE HYDROCHLORIDE)

NUBAIN 20 MG (NALBUPHINE HYDROCHLORIDE)

 

NUBAIN 20 MG (NALBUPHINE HYDROCHLORIDE), sold under the brand names Nubain and Nalpain among others, is a opioid analgesic which is used in the treatment of pain.It is given by injection into a vein, muscle, or fat.

Side effects of nalbuphine include sedation, sweatiness, clamminess, nausea, vomiting, dizziness, vertigo, dry mouth, and headache.Unlike other opioids, it has little to no capacity for euphoria or respiratory depression.It also has little to no incidence of dysphoria, dissociation, hallucinations, and related side effects at typical therapeutic doses. Nalbuphine is a mixed agonist/antagonist opioid modulator. Specifically, it acts as a moderate-efficacy partial agonist agonist or antagonist of the μ-opioid receptor (MOR) and as a high-efficacy partial agonist of the κ-opioid receptor (KOR), whereas it has relatively low affinity for the δ-opioid receptor (DOR) and sigma receptors.

Nalbuphine was discovered in 1965 and was introduced for medical use in the United States in 1979. It is marketed in many countries throughout the world.

Nubain Kinz 10mg/ml 1ml/Ampoule,

Nubain Kinz 20mg/ml 1ml/Ampoule

Nubain (Nalbuphine Hydrochloride) 10mg/ml 10ml/Vial

Nubain (Nalbuphine Hydrochloride) 20mg/ml 10ml/Vial

Nubain Kinz 10mg/ml 1ml/Ampoule

250 Ampoules………..$400

500 Ampoules………..$600

1000 Ampoules………$1000

2000 Ampoules………$1800

5000 Ampoules………$3500

Nubain Kinz 20mg/ml 1ml/Ampoule

250 Ampoules………..$500

500 Ampoules………..$850

1000 Ampoules………$1500

2000 Ampoules………$2500

5000 Ampoules………$5750

Nubain (Nalbuphine Hydrochloride) 10mg/ml 10ml/Vial

25 Vials…………$350

50 Vials…………$550

100 Vials……….$1000

200 Vials……….$1600

500 Vials……….$3500

1000 Vials……..$6000

5000 Vials……..$30000

Nubain (Nalbuphine Hydrochloride) 20mg/ml 10ml/Vial

25 Vials…………$500

50 Vials…………$800

100 Vials……….$1700

200 Vials……….$3000

500 Vials……….$6000

1000 Vials……..$10000

5000 Vials……..$50000

KINZ NALBUPHINE IS A SYNTHETIC AGONIST-ANTAGONIST OF THE PHENANTHRENE SERIES. IT IS CHEMICALLY RELATED TO BOTH THE WIDELY USED OPIOID , , AND THE POTENT OPIOID ANALGESIC, OXYMORPHONE. CHEMICALLY NALBUPHINE HYDROCHLORIDE IS 17-(CYCLOBUTYLMETHYL)-4,5Α-EPOXYMORPHINAN-3,6Α,14-TRIOL HYDROCHLORIDE. NALBUPHINE HYDROCHLORIDE MOLECULAR WEIGHT IS 393.91 AND IS SOLUBLE IN H2O (35.5 MG/ML @ 25ºC) AND ETHANOL (0.8%); INSOLUBLE IN CHCL3 AND ETHER. NALBUPHINE HYDROCHLORIDE HAS PKA VALUES OF 8.71 AND 9.96. THE MOLECULAR FORMULA IS C21H27NO4·HCL.

NUBAIN IS A STERILE SOLUTION SUITABLE FOR SUBCUTANEOUS, INTRAMUSCULAR, OR INTRAVENOUS INJECTION. NUBAIN IS AVAILABLE IN TWO CONCENTRATIONS, 10 MG AND 20 MG OF NALBUPHINE HYDROCHLORIDE PER ML. BOTH STRENGTHS IN 10 ML VIALS CONTAIN 0.94% SODIUM CITRATE HYDROUS, 1.26% CITRIC ACID ANHYDROUS, AND 0.2% OF A 9:1 MIXTURE OF METHYLPARABEN AND PROPYLPARABEN AS PRESERVATIVES; PH IS ADJUSTED, IF NECESSARY, TO 3.5 TO 3.7 WITH HYDROCHLORIC ACID. THE 10 MG/ML STRENGTH CONTAINS 0.2% SODIUM CHLORIDE.

NUBAIN IS ALSO AVAILABLE IN AMPULS IN A STERILE, PARABEN-FREE FORMULATION IN TWO CONCENTRATIONS, 10 MG AND 20 MG OF NALBUPHINE HYDROCHLORIDE PER ML. ONE ML OF EACH STRENGTH CONTAINS 0.94% SODIUM CITRATE HYDROUS, AND 1.26% CITRIC ACID ANHYDROUS; PH IS ADJUSTED, IF NECESSARY, TO 3.5 TO 3.7 WITH HYDROCHLORIC ACID. THE 10 MG/ML STRENGTH CONTAINS 0.2% SODIUM CHLORIDE.